Grasas y Aceites, Vol 69, No 3 (2018)

A novel antioxidant: 6,6'-(butane-1,1-diyl)bis(4-methylbenzene-1,2-diol)


https://doi.org/10.3989/gya.0344181

T. M. Olajide
School of Life Sciences, Shanghai University 333, China
orcid http://orcid.org/0000-0003-4751-8715

H. Pasdar
School of Life Sciences, Shanghai University 333, China
orcid http://orcid.org/0000-0002-6807-6090

X. C. Weng
School of Life Sciences, Shanghai University 333, China
orcid http://orcid.org/0000-0003-2047-1654

Abstract


A novel compound, 6,6'-(butane-1,1-diyl)bis(4-methylbenzene-1,2-diol) (BMB), was synthesized through an acid-catalyzed condensation reaction between 4-methylcatechol (HPC) and butyraldehyde. When evaluated by the Rancimat and deep frying methods, BMB exhibited a stronger antioxidant activity than TBHQ. Its DPPH radical scavenging activity was also fairly higher than TBHQ, but lower compared to its mother phenol, HPC, due to its relative ease of binding DPPH•. BMB had the strongest scavenging ability of the 4-methylcatechol analogues reported to date. It could be used effectively to retard lipid peroxidation in both moderate and high temperature food preparations.

Keywords


6,6'-(butane-1,1-diyl)bis(4-methylbenzene-1,2-diol); Acid-catalyzed condensation reaction; Antioxidant activity; Deep frying; HPC; TBHQ

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