Grasas y Aceites, Vol 51, No 1-2 (2000)

The lipid organisation of the cell membrane

S. Ladha
Institute of Food Research, Norwich Research Park, Colney, Norwich. UK. NR4 7UA., United Kingdom


Lipids and proteins in biological membranes are arranged in a mosaic of domains in the membrane. These domains represent small-scale heterogeneities in composition, shape and fluidity within the plane of the membrane, over the range of hundreds of nanometers to a few micrometers. They arise from the complex interactions of the heterogeneous mixtures of phospholipids, sterols, and proteins that make up all biological membranes.


Lipid composition; Lipid domains; Membrane; Phase separation

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