Grasas y Aceites, Vol 51, No 1-2 (2000)

The lipid organisation of the cell membrane


https://doi.org/10.3989/gya.2000.v51.i1-2.407

S. Ladha
Institute of Food Research, Norwich Research Park, Colney, Norwich. UK. NR4 7UA., United Kingdom

Abstract


Lipids and proteins in biological membranes are arranged in a mosaic of domains in the membrane. These domains represent small-scale heterogeneities in composition, shape and fluidity within the plane of the membrane, over the range of hundreds of nanometers to a few micrometers. They arise from the complex interactions of the heterogeneous mixtures of phospholipids, sterols, and proteins that make up all biological membranes.

Keywords


Lipid composition; Lipid domains; Membrane; Phase separation

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