Grasas y Aceites, Vol 61, No 3 (2010)

Antioxidant activity of flower, stem and leaf extracts of Ferula gummosa Boiss


https://doi.org/10.3989/gya.110809

Seyed Fazel Nabavi
Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences of Medical Sciences - Student Research Development Committee, Mazandaran University of Medical Sciences, Iran, Islamic Republic of

Mohammad Ali Ebrahimzadeh
Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences, Iran, Islamic Republic of

Seyed Mohammad Nabavi
Pharmaceutical Sciences Research Center, School of Pharmacy, Mazandaran University of Medical Sciences - Department of Biology, University of Mazandaran, Iran, Islamic Republic of

Bahman Eslami
Department of Biology, Islamic Azad University, Iran, Islamic Republic of

Abstract


The Antioxidant and antihemolytic activities of hydroalcoholic extracts of the flowers, stems and leaves of the Ferula gummosa Boiss were investigated employing different in vitro assay systems. Leaf extract showed better activity in DPPH radical scavenging. In addition it showed better activity in nitric oxide and H2O2 scavenging and Fe2+ chelating activity than the other parts. The extracts exhibited good antioxidant activity in linoleic acid system test but were not comparable with vitamin C (p< 0.001). The extracts showed weak reducing power activity. The F. gummosa stem extract showed better antihemolytic activity against H2O2 induced hemolysis. Among the extracts, the flowers had higher phenolic and flavonoid contents. This plant is very promising for further biochemical experiments.

Keywords


Antihemolytic; Antioxidant activity; Ferula gummosa; Flavonoid

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References


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