Potential of Annona muricata L. seed oil: phytochemical and nutritional characterization associated with non-toxicity

Authors

DOI:

https://doi.org/10.3989/gya.0777171

Keywords:

Acetogenins, Annona muricata seeds, Annonacin, Linoleic acid, Oleic acid

Abstract


The aim of this study was to evaluate the nutritional quality, phenolic compounds, fatty acid and antioxidant activity in vitro as well as a toxicological screening of A. muricata seed oil in vivo. The chemical composition and quantification of phenolic compounds were determined by the Adolfo Lutz Institute normative. The antioxidant activity was evaluated by DPPH, FRAP and ABTS methods. The oil was extracted by chloroform/ methanol and precipitated crude (AmPtO) and supernatant oils (AmSO) were obtained. The fatty acid profile was evaluated by gas chromatography and total compounds by HPLC-DAD. BALB/C mice received AmPtO and AmSO (0.5 and 1.0mL·Kg-1) for 14 days. Toxicity parameters were assessed. The major fatty acids in the oil were oleic (39.2%) and linoleic (33%). HPLC-DAD suggested the presence of acetogenins (annonacin: 595 [M-H]-), with a greater presence in AmPtO. The AmPtO group showed toxicity, which may be related to the acetogenin content in AmPtO. The AmSO group showed no toxicity and this oil has potential for food or medicinal use.

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Published

2018-03-30

How to Cite

1.
Pinto LC, de Souza CO, de Souza SA, da Silva HB, da Silva RR, Cerqueira-Lima AT, Teixeira TO, da Silva TM, Medeiros KC, Bittencourt M, Brandão HR, Druzian JI, Conceição AS, Lopes MV, Figueiredo CA. Potential of Annona muricata L. seed oil: phytochemical and nutritional characterization associated with non-toxicity. Grasas aceites [Internet]. 2018Mar.30 [cited 2024Mar.19];69(1):e234. Available from: https://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/1701

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Research