Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols

R. de la Puerta; R. Maestro Durán; V. Ruiz Gutiérrez

doi:10.3989/gya.1997.v48.i2.775

Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols

Authors

R. de la Puerta Dpto. Farmacia, Tecnología Farmacéutica y Farmacología, Facultad de Farmacia, Sevilla
R. Maestro Durán Instituto de la Grasa (C.S.I.C.).
V. Ruiz Gutiérrez Instituto de la Grasa (C.S.I.C.).

DOI:

https://doi.org/10.3989/gya.1997.v48.i2.775

Keywords:

Antiinflamatory activity, Sterol, Triterpene alcohol, Virgin olive oil.

Abstract

The fraction of sterols and triterpenic dialcohols from unsaponifiable of virgin olive oil has been tested for Its possible antiinflamatory activity. The topical administration of these products produced a potent antioedematous effect, in the auricular oedema induced by TPA (12-0-tetradecanoylphorbol acetate) in experimental animals. This test has been widely used to determine the antiinflamatory action of phospholipase A₂ inhibitors. The measure of myeloperoxidase, marker enzyme of the accumulation of neutrophils in the inflamed tissue, demonstrated a significant reduction of the cellular infiltration produced by assayed fraction.

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Published

1997-04-30

How to Cite

de la Puerta R, Maestro Durán R, Ruiz Gutiérrez V. Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols. Grasas aceites [Internet]. 1997Apr.30 [cited 2024Apr.19];48(2):93-5. Available from: https://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/775

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Issue

Vol. 48 No. 2 (1997)

Section

Research

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