Effects of diets rich in monounsaturated fatty acids on the management and prevention of insulin resistance: A systematic review





Metabolic syndrome, Monounsaturated fatty acids, Obesity, Systematic review


Insulin resistance (IR), which is linked to obesity, is a mechanism associated with metabolic diseases, mainly type 2 diabetes mellitus. Studies have shown that monounsaturated fatty acids (MUFAs) have anti-inflammatory and anti-oxidative properties which positively affect IR. This systematic review examined the effects of MUFAs from different sources on IR in obese or overweight patients with or without metabolic syndrome. A search was carried out in the PubMed/Medline and Bireme/VHL databases, and data from 16 studies were analysed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The intervention time ranged from 1 day to 5.2 years. All participants were overweight or obese; some had central obesity, a moderate risk of cardiovascular disease, low high-density lipoprotein levels, altered fasting glucose levels, prediabetes or type 2 diabetes mellitus. This systematic review provides evidence that MUFA-rich diets can improve IR.


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How to Cite

Ramos E, Lima M, Azevedo A, Lopes M, Moreira A, Souza C. Effects of diets rich in monounsaturated fatty acids on the management and prevention of insulin resistance: A systematic review. grasasaceites [Internet]. 2023Oct.10 [cited 2023Dec.5];74(3):e522. Available from: https://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/2065