Effects of diets rich in monounsaturated fatty acids on the management and prevention of insulin resistance: A systematic review

E.L.L.  Ramos; M.F.C.  Lima; A.C.S.F.  Azevedo; M.G.F. Lopes; A.P.B. Moreira; C.T. Souza

doi:10.3989/gya.1125212

Autores/as

E.L.L. Ramos Research Centre in Nutrients and Physical Exercise Applied to Metabolic Syndrome, Medicine School, Universidade Federal de Juiz de Fora https://orcid.org/0000-0002-3850-6379
M.F.C. Lima Research Centre in Nutrients and Physical Exercise Applied to Metabolic Syndrome, Medicine School, Universidade Federal de Juiz de Fora https://orcid.org/0000-0002-5735-4411
A.C.S.F. Azevedo Research Centre in Nutrients and Physical Exercise Applied to Metabolic Syndrome, Medicine School, Universidade Federal de Juiz de Fora https://orcid.org/0000-0001-8642-8347
M.G.F. Lopes Research Centre in Nutrients and Physical Exercise Applied to Metabolic Syndrome, Medicine School, Universidade Federal de Juiz de Fora https://orcid.org/0000-0003-4035-8448
A.P.B. Moreira Department of Nutrition, Biological Sciences Institute, Universidade Federal de Juiz de Fora https://orcid.org/0000-0001-5909-1996
C.T. Souza Research Centre in Nutrients and Physical Exercise Applied to Metabolic Syndrome, Medicine School, Universidade Federal de Juiz de Fora https://orcid.org/0000-0003-4904-5675

DOI:

https://doi.org/10.3989/gya.1125212

Palabras clave:

Ácidos grasos monoinsaturados, Obesidad, Revisión sistemática, Síndrome metabólico

Resumen

La resistencia a la insulina (RI), que está ligada a la obesidad, es un mecanismo asociado a enfermedades metabólicas, principalmente a la diabetes mellitus tipo 2. Los estudios han demostrado que los ácidos grasos monoinsaturados (AGMI) tienen propiedades antiinflamatorias y antioxidantes, que afectan positivamente a la RI. Esta revisión sistemática examinó los efectos de los AGMI de diferentes fuentes sobre la RI en pacientes obesos o con sobrepeso con o sin síndrome metabólico. Se realizó una búsqueda en las bases de datos PubMed/Medline y Bireme/VHL, y se analizaron los datos de 16 estudios de acuerdo con las pautas Preferred Reporting Items for Systematic Reviews and Meta-Analyses. El tiempo de intervención osciló entre 1 día y 5,2 años. Todos los participantes tenían sobrepeso u obesidad; algunos tenían obesidad central, riesgo moderado de enfermedad cardiovascular, niveles bajos de lipoproteínas de alta densidad, niveles alterados de glucosa en ayunas, prediabetes o diabetes mellitus tipo 2. Esta revisión sistemática proporciona evidencia de que las dietas ricas en MUFA pueden mejorar la RI.

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