Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols

R. de la Puerta; R. Maestro Durán; V. Ruiz Gutiérrez

doi:10.3989/gya.1997.v48.i2.775

Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols

Authors

R. de la Puerta Dpto. Farmacia, Tecnología Farmacéutica y Farmacología, Facultad de Farmacia, Sevilla
R. Maestro Durán Instituto de la Grasa (C.S.I.C.).
V. Ruiz Gutiérrez Instituto de la Grasa (C.S.I.C.).

DOI:

https://doi.org/10.3989/gya.1997.v48.i2.775

Keywords:

Antiinflamatory activity, Sterol, Triterpene alcohol, Virgin olive oil.

Abstract

The fraction of sterols and triterpenic dialcohols from unsaponifiable of virgin olive oil has been tested for Its possible antiinflamatory activity. The topical administration of these products produced a potent antioedematous effect, in the auricular oedema induced by TPA (12-0-tetradecanoylphorbol acetate) in experimental animals. This test has been widely used to determine the antiinflamatory action of phospholipase A₂ inhibitors. The measure of myeloperoxidase, marker enzyme of the accumulation of neutrophils in the inflamed tissue, demonstrated a significant reduction of the cellular infiltration produced by assayed fraction.

Downloads

Download data is not yet available.

Downloads

Published

1997-04-30

How to Cite

de la Puerta R, Maestro Durán R, Ruiz Gutiérrez V. Pharmacological activity of the fraction isolated from virgin olive oil containing the sterols and triterpenic alcohols. grasasaceites [Internet]. 1997Apr.30 [cited 2023Sep.30];48(2):93-5. Available from: https://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/775

Download Citation

Issue

Vol. 48 No. 2 (1997)

Section

Research

License

This work is licensed under a Creative Commons Attribution 4.0 International License.

© CSIC. Manuscripts published in both the printed and online versions of this Journal are the property of Consejo Superior de Investigaciones Científicas, and quoting this source is a requirement for any partial or full reproduction.

All contents of this electronic edition, except where otherwise noted, are distributed under a “Creative Commons Attribution 4.0 International” (CC BY 4.0) License. You may read here the basic information and the legal text of the license. The indication of the CC BY 4.0 License must be expressly stated in this way when necessary.

Self-archiving in repositories, personal webpages or similar, of any version other than the published by the Editor, is not allowed.