Chemical compositon, antibacterial and antioxidant activities of Cnidium silaifolium ssp. orientale (Boiss.) Tutin essential oils

Authors

DOI:

https://doi.org/10.3989/gya.1146192

Keywords:

Antimicrobial, Antioxidant, Apiaceae, Cnidium silaifolium ssp. orientale

Abstract


The chemical compositions of the essential oils (EOs) obtained by hydrodistillation from different parts of Cnidium silaifolium ssp. orientale (Boiss.) Tutin were analyzed both by GC-FID and GC/MS, simultaneously. One hundred nine compounds representing 90.1% of the total volatiles in the EOs were identified with the main characteristic compounds α-pinene (50.3%) in the root, germacrene D (20.3%) in the fruit, and β-caryophyllene (18.7%) in the aerial parts of C. silaifolium ssp. orientale. The antimicrobial activity against human pathogenic Gram-negative and Gram-positive bacteria was evaluated by the in vitro microdilution method. Antibacterial succeptibility was observed from the root and aerial part EOs against Staphylococcus aureus (0.039 and 0.156 mg/mL, respectively); while the fruit EO was most effective against Bacillus cereus at 0.07 mg/mL. The antioxidant capacities of the EOs were also evaluated by in vitro DPPH• and ABTS•+ scavenging assays, where no significant activity was observed compared to ascorbic acid and Trolox.

Downloads

Download data is not yet available.

References

Aligiannis N, Kalpoutzakis E, Kyriakopoulou I, Mitaku S, Chinou IB. 2004. Essential oils of Phlomis species growing in Greece: Chemical composition and antimicrobial activity. Flavour Fragr. J. 19, 320-324. https://doi.org/10.1002/ffj.1305

Arici M, Sagdic O, Gecgel U. 2005. Antibacterial effect of Turkish black cumin (Nigella sativa L.) oils. Grasas Aceites 56, 259-262. https://doi.org/10.3989/gya.2005.v56.i4.90

Başer KHC, Buchbauer G. 2016. Handbook of Essential Oils Science, Technology and Applications. 2nd edition. London, CRC Press, 121-130. https://doi.org/10.1201/b19393

Demirci F, Karaca N, Tekin M, Demirci B. 2018. Anti-inflammatory and antibacterial evaluation of Thymus sipyleus Boiss. subsp. sipyleus var. sipyleus essential oil against rhinosinusitis pathogens. Microb. Pathog. 122, 117-121. https://doi.org/10.1016/j.micpath.2018.06.025 PMid:29908309

Hong H, An JC, De La Cruz JF, Hwang SG. 2017. Cnidium officinale makino extract induces apoptosis through activation of caspase-3 and p53 in human liver cancer HepG2 cells. Exp. Ther. Med. 14, 3191-3197. https://doi.org/10.3892/etm.2017.4916 PMid:28966688 PMCid:PMC5615224

Jeong JB, Ju SY, Park JH, Lee JR, Yun KW, Kwon ST, Lim JH, Chung GY, Jeong HJ. 2009. Antioxidant activity in essential oils of Cnidium officinale makino and Ligusticum chuanxiong hort and their inhibitory effects on DNA damage and apoptosis induced by ultraviolet B in mammalian cell. Cancer Epidemiol. 33, 41-46. https://doi.org/10.1016/j.canep.2009.04.010 PMid:19679046

Kapetanos C, Karioti A, Bojović S, Marin P, Veljić M, Skaltsa H. 2008. Chemical and principal-component analyses of the essential oils of Apioideae taxa (Apiaceae) from Central Balkan. Chem Biodivers. 5, 101-119. https://doi.org/10.1002/cbdv.200890000 PMid:18205131

Karadağ AE, Demirci B, Çaşkurlu A, Demirci F, Okur ME, Orak D, Sipahi H, Başer KHC. 2019. In vitro antibacterial, antioxidant, anti-inflammatory and analgesic evaluation of Rosmarinus officinalis L. flower extract fractions. South African J. Bot. 125, 214-220. https://doi.org/10.1016/j.sajb.2019.07.039

Karadag AE, Demirci B, Cecen O, Tosun F. 2019. Chemical characterization of Glaucosciadium cordifolium (Boiss.) B.L. Burtt and P.H. Davis essential oils and their antimicrobial, and antioxidant activities. Istanbul J. Pharm. 49, 77-80.

Kim K-T, Kim M-H, Park J-H, Lee J-Y, Cho H-J, Yoon I-S, Kim D-D. 2018. Microemulsion-based hydrogels for enhancing epidermal/dermal deposition of topically administered 20(S)-protopanaxadiol: in vitro and in vivo evaluation studies. J. Ginseng Res. 42, 512-523. https://doi.org/10.1016/j.jgr.2017.07.005 PMid:30337812 PMCid:PMC6190503

Li YM, Jia M, Li HQ, Zhang ND, Wen X, Rahman K, Zhang QY, Qin LP. 2015. Cnidium monnieri: A review of traditional uses, phytochemical and ethnopharmacological properties. Am. J. Chin. Med. 43, 835-877. https://doi.org/10.1142/S0192415X15500500 PMid:26243582

Lim EG, Kim GT, Kim BM, Kim EJ, Kim SY, Kim YM. 2018. Ethanol extract from Cnidium monnieri (L.) Cusson induces cell cycle arrest and apoptosis via regulation of the p53-independent pathway in HepG2 and Hep3B hepatocellular carcinoma cells. Mol. Med. Rep. 17, 2572-2580. https://doi.org/10.3892/mmr.2017.8183

Oh H, Kim JS, Song EK, Cho H, Kim DH, Park SE, Lee HS, Kim YC. 2002. Sesquiterpenes with hepatoprotective activity from Cnidium monnieri on tacrine-induced cytotoxicity in Hep G2 cells. Planta Med. 68, 748-749. https://doi.org/10.1055/s-2002-33796 PMid:12221602

Polat T, Özer H, Cakir A, Kandemir A, Mete E, Özturk E, Yildiz G. 2011. Volatile Constituents of Cnidium silaifolium (Jacq.) Simonkai subsp. orientale (Boiss.) Tutin from Turkey. J. Essent. Oil-Bearing Plants 14, 453-457. https://doi.org/10.1080/0972060X.2011.10643600

Selim SA. 2011. Chemical composition, antioxidant and antimicrobial activity of the essential oil and methanol extract of the egyptian lemongrass cymbopogon proximus stapf. Grasas Aceites 62, 55-61. https://doi.org/10.3989/gya.033810

Sim Y, Shin S. 2014. Antibacterial activities of the essential oil from the leaves and rhizomes of Cnidium officinale Makino. J. Essent. Oil Res. 26, 452-457. https://doi.org/10.1080/10412905.2014.951456

Tatsadjieu LN, Essia Ngang JJ, Ngassoum MB, Etoa FX. 2003. Antibacterial and antifungal activity of Xylopia aethiopica, Monodora myristica, Zanthoxylum xanthoxyloïdes and Zanthoxylum leprieurii from Cameroon. Fitoterapia 74, 469-472. https://doi.org/10.1016/S0367-326X(03)00067-4

Tran HNK, Cao TQ, Kim JA, Youn UJ, Kim S, Woo MH, Min BS. 2018. Anti-inflammatory activity of compounds from the rhizome of Cnidium officinale. Arch. Pharm. Res. 41, 977-985. https://doi.org/10.1007/s12272-018-1048-9 PMid:29961195

Yüzbaşıoğlu S, Altınözlü H, Kandemir A, Özbek MU. 2018. Flora of Kemaliye (Erzincan) District. Hacettepe J. Biol. Chem. 4, 533-557. https://doi.org/10.15671/HJBC.2018.261

Published

2021-06-03

How to Cite

1.
Karadağ A, Demirci B, Çeçen Ö., Tosun F, Demirci F. Chemical compositon, antibacterial and antioxidant activities of Cnidium silaifolium ssp. orientale (Boiss.) Tutin essential oils. Grasas aceites [Internet]. 2021Jun.3 [cited 2024Apr.18];72(2):e403. Available from: https://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/1874

Issue

Section

Research