Chemical compositon, antibacterial and antioxidant activities of Cnidium silaifolium ssp. orientale (Boiss.) Tutin essential oils

A.E.  Karadağ; B.  Demirci; Ö.  Çeçen; F.  Tosun; F.  Demirci

doi:10.3989/gya.1146192

Autores/as

A.E. Karadağ School of Pharmacy, Department of Pharmacognosy, Istanbul Medipol University - Graduate School of Health Sciences, Department of Pharmacognosy, Anadolu University, https://orcid.org/0000-0002-3412-0807
B. Demirci Faculty of Pharmacy, Department of Pharmacognosy, Anadolu University https://orcid.org/0000-0003-2343-746X
Ö. Çeçen Department of Plant and Animal Production, Medical and Aromatic Plants Programme, Ermenek Vocational High School, Karamanoğlu Mehmetbey University https://orcid.org/0000-0002-1315-9876
F. Tosun School of Pharmacy, Department of Pharmacognosy, Istanbul Medipol University https://orcid.org/0000-0003-2533-5141
F. Demirci Faculty of Pharmacy, Department of Pharmacognosy, Anadolu University - Faculty of Pharmacy, Eastern Mediterranean University https://orcid.org/0000-0003-1497-3017

DOI:

https://doi.org/10.3989/gya.1146192

Palabras clave:

Antimicrobiano, Antioxidante, Apiacea, Cnidium silaifolium ssp. orientale

Resumen

Se analizó por GC-FID y GC-MS la composición química de los aceites esenciales (AE) obtenidos por hidrodestilación de diferentes partes de Cnidium silaifolium ssp. orientale (Boiss.) tutin. Ciento nueve compuestos, que representan el 90.1% del total de volátiles de los AE, se identificaron. Los compuestos característicos principales fueron α-pineno (50.3%) en la raíz, germacreno D (20.3%) en la fruta y β-cariofileno (18.7%) en las partes aéreas de C. silaifolium ssp. orientale. La actividad antimicrobiana contra bacterias Gram negativas y Gram positivas patógenas humanas se evaluó mediante el método de microdilución in vitro. La susceptibilidad antibacteriana contra Staphylococcus aureusse observó desde la raíz a la parte aérea AEs (0.039 y 0.156 mg/mL, respectivamente), mientras que la fruta EO fue más efectiva contra Bacillus cereus a 0.07 mg/mL. La capacidad antioxidante de los AE también se evaluó mediante ensayos de eliminación in vitro de DPPH• y ABTS•+, donde no se observó actividad significativa en comparación con el ácido ascórbico y Trolox.

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