Lipophilic components and evaluation of the cytotoxic and antioxidant activities of <em>Impatiens glandulifera</em> Royle and <em>Impatiens noli – tangere</em> L. (Balsaminaceae)

K. Szewczyk; R. Bonikowski; A. Maciąg-Krajewska; J. Abramek; A. Bogucka-Kocka

doi:10.3989/gya.0234181

Autores/as

K. Szewczyk Department of Pharmaceutical Botany, Medical University of Lublin https://orcid.org/0000-0003-4884-9110
R. Bonikowski Łódź University of Technology, Faculty of Biotechnology and Food Sciences, Institute of General Food Chemistry https://orcid.org/0000-0003-3327-8984
A. Maciąg-Krajewska Łódź University of Technology, Faculty of Biotechnology and Food Sciences, Institute of General Food Chemistry https://orcid.org/0000-0001-9892-1219
J. Abramek Department of Biology and Genetics, Medical University of Lublin https://orcid.org/0000-0001-7925-4350
A. Bogucka-Kocka Department of Biology and Genetics, Medical University of Lublin https://orcid.org/0000-0001-8473-7429

DOI:

https://doi.org/10.3989/gya.0234181

Palabras clave:

Ácidos grasos, Antioxidante, Cytotoxicidad, Fitoesteroless, Impatiens, Triterpenoides

Resumen

La composición química de las fracciones lipofílicas, centrada en los ácidos grasos, triterpenoides y esteroles de las partes aéreas, raíces y semillas de Impatiens glandulifera Royle e Impatient. noli-tangere L. se analizaron por cromatografía de gases-espectrometría de masas (GC-MS). La mayoría de los compuestos identificados son nuevos para estas especies. Los ácidos a-linolénico, oleico y palmítico fueron los más abundantes en las fracciones de ácidos grasos, β-amirina y 5a-lup-20 (29)-en-3β-ol en las fracciones triterpenoides, y β-sitosterol, espinasterol y condriplasterol en las fracciones de esteroles. Las fracciones de ácidos grasos y triterpenos mostraron una fuerte actividad antioxidante, similar a los controles positivos. Además, la fracción triterpenoidea de las semillas de I. noli-tangere inhibió significativamente las células de leucemia humana HL-60. Otras fracciones mostraron citotoxicidad moderada. El presente estudio sugiere que I. glandulifera e I. noli-tangere son la buena fuente de ácidos grasos omega-3, y podrían considerarse antioxidantes y agentes quimiopreventivos.

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