Potential of <em>Annona muricata</em> L. seed oil: phytochemical and nutritional characterization associated with non-toxicity

L. C. Pinto; C. O. de Souza; S. A. de Souza; H. B. da Silva; R. R. da Silva; A. T. Cerqueira-Lima; T. O. Teixeira; T. M.S. da Silva; K. C.P. Medeiros; M. Bittencourt; H. R. Brandão; J. I. Druzian; A. S. Conceição; M. V. Lopes; C. A. Figueiredo

doi:10.3989/gya.0777171

Autores/as

L. C. Pinto Department of Food Science, School of Nutrition, Federal University of Bahia https://orcid.org/0000-0001-7470-7074
C. O. de Souza Faculty of Pharmacy, Federal University of Bahia https://orcid.org/0000-0002-8028-5418
S. A. de Souza Laboratory of Phytochemistry Bioprospecting, Federal Rural University of Pernambuco https://orcid.org/0000-0001-9689-7614
H. B. da Silva Institute of Health Sciences, Federal University of Bahia https://orcid.org/0000-0003-1585-9099
R. R. da Silva Department of Life Sciences, State University of Bahia https://orcid.org/0000-0002-3422-0453
A. T. Cerqueira-Lima Institute of Health Sciences, Federal University of Bahia https://orcid.org/0000-0001-7991-4005
T. O. Teixeira Institute of Health Sciences, Federal University of Bahia https://orcid.org/0000-0001-7998-2569
T. M.S. da Silva Laboratory of Phytochemistry Bioprospecting, Federal Rural University of Pernambuco https://orcid.org/0000-0003-1887-2598
K. C.P. Medeiros Federal University of Rio Grande do Norte https://orcid.org/0000-0002-7784-0740
M. Bittencourt Veterinary Hospital UNIME (HOSVET). Metropolitan Union of Education and Culture (UNIME) https://orcid.org/0000-0002-9893-173X
H. R. Brandão Veterinary Hospital UNIME (HOSVET). Metropolitan Union of Education and Culture (UNIME) https://orcid.org/0000-0001-9061-7749
J. I. Druzian Faculty of Pharmacy, Federal University of Bahia https://orcid.org/0000-0001-8940-6098
A. S. Conceição University of Bahia State, Department of Education, Herbarium of the State University of Bahia (HUNEB) https://orcid.org/0000-0002-8800-422X
M. V. Lopes Department of Life Sciences, State University of Bahia https://orcid.org/0000-0001-5985-8755
C. A. Figueiredo Institute of Health Sciences, Federal University of Bahia https://orcid.org/0000-0003-1356-6188

DOI:

https://doi.org/10.3989/gya.0777171

Palabras clave:

Acetogeninas, Ácido linoleico, Ácido oleico, Anonacina, Semillas de Annona muricata

Resumen

El objetivo de este estudio fue evaluar la calidad nutricional, compuestos fenólicos, ácidos grasos, actividad antioxidante in vitro y evaluación toxicológica del aceite de las semillas de la Annona muricata. La composición química y los compuestos fenólicos se determinaron de acuerdo con las normas del Instituto Adolfo Lutz y la actividad antioxidante por métodos de DPPH, FRAP y ABTS. El aceite fue extraído con cloroformo/metanol obteniéndose un precipitado crudo (AmPtO) y un aceite sobrenadante (AmSO). El perfil de ácidos grasos fue evaluado por cromatografía gaseosa y los compuestos fitoquímicos mediante HPLC-DAD. BALB/C recibieron AmPtO y AmSO (0,5 y 1,0 mL·kg^-1) durante 14 días. Se evaluaron los parámetros bioquímicos e histopatológicos. Los ácidos grasos principales fueron oleico (39,2%) y linoleico (33%). HPLC-DAD indicó la presencia de acetogeninas, particularmente anonacina (595 [M-H]-), principalmente en AmPtO. AmPtO presentó toxicidad y esto puede estar relacionado con las acetogeninas. AmSO no presentó toxicidad y tiene potencial para la alimentación o uso medicinal.

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