Virgin olive oil and cholesterol distribution and transbilayer movement in human erythrocyte membrane.
DOI:
https://doi.org/10.3989/gya.1998.v49.i2.713Keywords:
Arterial blood pressure, Cholesterol distribution, Cholesterol transbilayer, High oleic sunflower oil, Humans, Sodium-lithium countertransport, Virgin olive oil.Abstract
The influence of virgin olive oil intake (with regard to the ingestion of high-oleic sunflower oil) on cholesterol distribution and transbilayer movement in the erythrocyte membrane of healthy subjects and hypertensive patients (with or without concomitant hypercholesterolaemia) was studied. The activity of erythrocyte sodium-lithium countertransport and blood pressure were also determined. The study was conducted over two 4-week periods, with a washout (4-week) period between both monounsaturated diets. Olive oil (but not high-oleic sunflower oil) was able to reduce the erythrocyte sodium-lithium countertransport activity, to normalize the erythrocyte membrane cholesterol distribution and transbilayer movement, and to significantly diminish the systolic and diastolic Wood pressures in hypertensive patients. Our data indicate that olive oil enriched-diet may modulate and/or partially prevent the alteration of those pathogenic parameters related to human hypertension and Cardiovascular Pathology. These processes cannot be exclusively ascribed to the content of oleic acid in virgin olive oil.
Downloads
Download data is not yet available.
Downloads
Published
1998-04-30
How to Cite
1.
Muriana FJG, Ruiz Gutiérrez V. Virgin olive oil and cholesterol distribution and transbilayer movement in human erythrocyte membrane. Grasas aceites [Internet]. 1998Apr.30 [cited 2024Jul.27];49(2):139-50. Available from: https://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/713
Issue
Section
Research
License
Copyright (c) 1998 Consejo Superior de Investigaciones Científicas (CSIC)
This work is licensed under a Creative Commons Attribution 4.0 International License.
© CSIC. Manuscripts published in both the printed and online versions of this Journal are the property of Consejo Superior de Investigaciones Científicas, and quoting this source is a requirement for any partial or full reproduction.All contents of this electronic edition, except where otherwise noted, are distributed under a “Creative Commons Attribution 4.0 International” (CC BY 4.0) License. You may read here the basic information and the legal text of the license. The indication of the CC BY 4.0 License must be expressly stated in this way when necessary.
Self-archiving in repositories, personal webpages or similar, of any version other than the published by the Editor, is not allowed.