Stearic acid: a possible substitute for trans fatty acids from industrial origin


  • Alfonso Valenzuela Instituto de Nutrición y Tecnología de los Alimentos (INTA), Universidad de Chile
  • Bernadette Delplanque Laboratoire de Neuroendocrinologie Moléculaire de la Prise Alimentaire (NMPA) UMR 1197, Université Paris Sud
  • Marcelo Tavella Programa de Prevención del Infarto en Argentina - INIBIOLP, Universidad Nacional de La Plata



Alternatives to hydrogenated fats, Cardiovascular health, “Neutral” metabolic effect, Stearic acid, trans Isomers


Trans isomers, contained in partially hydrogenated oils, which are used in the food industry, have been questioned and nowadays trends are heading towards reducing their consumption. The food industry is facing a dilemma, since in order to remove trans fatty acids, hydrogenated fats should be eliminated and replaced by fats rich in saturated fatty acids. Scientific research has shown that saturated fatty acids have negative effects on the lipid profile and its consumption is associated with a higher cardiovascular risk. Therefore it is recommended to avoid their consumption. Nevertheless, not all fatty acids behave in the same way, with stearic acid (18:0) the exception. Stearic acid has a low level of intestinal absorption and its intake does not negatively modify the lipid profile. For this reason, it is considered a “neutral” fatty acid with regard to cardiovascular health. B-100 apolipoprotein, whose levels determine plasma VLDL and LDL concentration (triglycerides and cholesterol carriers, respectively), is not modified by diets which provide up to 7% of the energy as stearic acid. Markers of cardiovascular risk, such as activation of platelet aggregation factors or C-reactive protein levels, are not modified by diets providing stearic acid, as occurs with other saturated fatty acids. The confirmation of the “neutral” effect of stearic acid represents a perspective for the development of fats with high contents of this fatty acid to replace hydrogenated fats containing trans isomers. The present review discusses these aspects.


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How to Cite

Valenzuela A, Delplanque B, Tavella M. Stearic acid: a possible substitute for trans fatty acids from industrial origin. grasasaceites [Internet]. 2011Jun.30 [cited 2022Nov.26];62(2):131-8. Available from: