Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest

Authors

  • A. M. F. Eissa Chemistry Department, Faculty of Science, Benha University
  • R. El-Sayed Chemistry Department, Faculty of Science, Benha University

DOI:

https://doi.org/10.3989/gya.2007.v58.i1.4

Keywords:

Antimicrobial activity, Surface activity, Synthesis

Abstract


The reaction of 2-hydroxyheptadecanoyl chloride (2) and anthranilic acid gave 2-(1-hydroxyheptadecyl)-4H-3,1-benzoxazin-4-one (3) which was used as starting material to synthesize some condensed and non-condensed heterocyclic compounds by a reaction with nitrogen nucleophiles (e.g., hydrazine hydrate, and formamide). The subsequent reaction of the synthetic products with different amounts of propylene oxide gave a novel group of nonionic compounds having a double function as antibacterial and surface active agents which may serve in the manufacturing of drugs, cosmetics, pesticides or as antibacterial and/or antifungal products. The surface active properties such as surface and interfacial tensions, cloud point, foaming height, wetting time, and emulsification power were determined. Antimicrobial and biodegradability were also screened.

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References

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Published

2007-03-30

How to Cite

1.
Eissa AMF, El-Sayed R. Synthesis and evaluation of ?-hydroxy fatty acid-derived heterocyclic compounds with potential industrial interest. grasasaceites [Internet]. 2007Mar.30 [cited 2022Dec.6];58(1):20-8. Available from: https://grasasyaceites.revistas.csic.es/index.php/grasasyaceites/article/view/4

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Research